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Curr Opin Biotechnol. 2012 Oct;23(5):744-50. doi: 10.1016/j.copbio.2011.12.019. Epub 2012 Jan 4.

Alternative biofuel production in non-natural hosts.

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  • 1Department of Chemistry, University of California, Davis, One Shields Ave, Davis, CA 95616, USA.


Global energy and environmental concerns have stimulated increased efforts in synthesizing petroleum-derived products from renewable resources. Biological production of metabolites for fuel is increasingly becoming a feasible, renewable, environmentally sound alternative. However, many of these chemicals are not highly produced in any known native organism. Here we review the current progress of modifying microorganisms with heterogeneous elements for the production of biofuels. This strategy has been extensively employed in a variety of hosts for the development of production of various alcohols, fatty acids, alkenes and alkanes.

Published by Elsevier Ltd.

[PubMed - indexed for MEDLINE]
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