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Cell. 2012 Jan 20;148(1-2):19-21. doi: 10.1016/j.cell.2011.12.016. Epub 2012 Jan 5.

Chimeric primates: embryonic stem cells need not apply.

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  • 1California Institute for Regenerative Medicine, 210 King Street, San Francisco, CA 94107, USA.


In this issue, Tachibana et al. report the generation of the first chimeras from a nonhuman primate, the rhesus monkey. Unlike mice, rhesus chimeras fail to form when embryonic stem cells are injected into blastocysts. Instead, chimera formation is achieved by aggregation of several four-cell embryos.

Copyright © 2012 Elsevier Inc. All rights reserved.

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