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J Biosci Bioeng. 2012 Apr;113(4):526-8. doi: 10.1016/j.jbiosc.2011.11.028. Epub 2012 Jan 4.

Understanding the mechanism of heat stress tolerance caused by high trehalose accumulation in Saccharomyces cerevisiae using DNA microarray.

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  • 1Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita,Osaka 565-0871, Japan.


DNA microarray analysis was performed to examine the stress tolerance mechanism of a Saccharomyces cerevisiae recombinant strain exhibiting high trehalose accumulation and heat stress tolerance. Results suggest that the upregulation of sugar transporter genes is one of the key events for heat stress tolerance of the recombinant strain.

Copyright © 2011 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

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