Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Case Rep Ophthalmol. 2011 Sep;2(3):360-6. doi: 10.1159/000334784. Epub 2011 Dec 2.

Exophthalmos as a first manifestation of small cell lung cancer: a long-term follow-up.

Author information

  • 11st Pulmonary Department, University of Thessalia, Larissa, Greece.


Small cell lung cancer is characterized by rapid growth and early metastasis. Despite its sensitivity to cytotoxic therapy, until now treatments have failed to control or cure this disease in most patients. Orbital metastases are a rare manifestation of systemic malignancies. Breast and lung cancers represent more than two thirds of the primary cancer sites. Metastases to the eye and orbit develop in approximately 0.7-12% of patients with lung cancer. Here, we report a rare case of exophthalmos as the first manifestation of a metastatic carcinoma due to small cell lung cancer, and a 6-months follow-up with complete exophthalmic response to chemotherapy.


Exophthalmos; Lung cancer; Orbital metastasis

Free PMC Article

Images from this publication.See all images (4)Free text

Fig. 1
Fig. 2
Fig. 3
Fig. 4
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Icon for S. Karger AG, Basel, Switzerland Icon for PubMed Central
    Loading ...
    Write to the Help Desk