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    Biol Lett. 2012 Jun 23;8(3):446-9. Epub 2012 Jan 4.

    Identification of two voltage-dependent anion channel-like protein sequences conserved in Kinetoplastida.

    Source

    Department of Biosciences, Molecular Cell Biology of Plants, Goethe University Frankfurt, , 60438 Frankfurt, Hesse, Germany.

    Abstract

    The eukaryotic porin superfamily consists of two families, voltage-dependent anion channel (VDAC) and Tom40, which are both located in the mitochondrial outer membrane. In Trypanosoma brucei, only a single member of the VDAC family has been described. We report the detection of two additional eukaryotic porin-like sequences in T. brucei. By bioinformatic means, we classify both as putative VDAC isoforms.

    PMID:
    22219392
    [PubMed - in process]

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