Assignment of the human nicotinic acetylcholine re...[Ann Hum Genet. 1990]

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1: Ann Hum Genet. 1990 Jul;54(Pt 3):199-208.Links

Assignment of the human nicotinic acetylcholine receptor genes: the alpha and delta subunit genes to chromosome 2 and the beta subunit gene to chromosome 17.

Beeson D, Jeremiah S, West LF, Povey S, Newsom-Davis J.

Institute for Molecular Medicine, John Radcliffe Hospital, Oxford.

The chromosomal assignments of the genes coding for the alpha, beta and delta subunits of the human nicotinic acetylcholine receptor have been determined from a panel of somatic cell hybrids and by direct in situ hybridization. The results localize CHRNA to 2q24-2q32. CHRNB to 17p11-17p12, and CHRND to chromosome 2q33-2qter.

PMID: 2221824 [PubMed - indexed for MEDLINE]

Localization of the acetylcholine receptor gamma subunit gene to human chromosome 2q32----qter.
Cytogenet Cell Genet. 1989; 52(3-4):124-7.

[Cytogenet Cell Genet. 1989]
Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans.
Genomics. 1992 Aug; 13(4):962-7.

[Genomics. 1992]
Five subunit genes of the human muscle nicotinic acetylcholine receptor are mapped to two linkage groups on chromosomes 2 and 17.
Genomics. 1993 Sep; 17(3):642-50.

[Genomics. 1993]
The genes coding for phosphoenolpyruvate carboxykinase-1 (PCK1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) map to human chromosome 20, extending the known region of homology with mouse chromosome 2.
Ann Hum Genet. 1992 Oct; 56(Pt 4):289-93.

[Ann Hum Genet. 1992]
Review[Identification of the breakpoint-flanking markers on chromosomes 1 and 17 of a constitutional translocation T(1;17)(P36;Q12-21) in a patient with neuroblastoma]
Verh K Acad Geneeskd Belg. 1995; 57(5):389-422.

[Verh K Acad Geneeskd Belg. 1995]
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Cited by 1 PubMed Central article

Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.
Liang Y, Wang A, Probst FJ, Arhya IN, Barber TD, Chen KS, Deshmukh D, Dolan DF, Hinnant JT, Carter LE, et al. Am J Hum Genet. 1998 Apr; 62(4):904-15.

[Am J Hum Genet. 1998]

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Assignment of the human nicotinic acetylcholine receptor genes: the alpha and delta subunit genes to chromosome 2 and the beta subunit gene to chromosome 17.

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