Format

Send to

Choose Destination
See comment in PubMed Commons below
Ann Intern Med. 1990 Nov 1;113(9):684-702.

Exercise thallium-201 scintigraphy in the diagnosis and prognosis of coronary artery disease.

Author information

  • 1Cedars-Sinai Medical Center, Los Angeles, California.

Abstract

OBJECTIVE:

To determine the discriminant accuracy of exercise thallium-201 myocardial perfusion scintigraphy for the diagnosis and prognosis of patients with known or suspected coronary artery disease.

DATA IDENTIFICATION:

A survey of the National Library of Medicine MEDLINE database.

STUDY SELECTION:

The key medical subject headings used were coronary disease, myocardial infarction, radionuclide imaging, and thallium. A total of 122 retrieved studies were considered relevant and were reviewed in depth.

DATA EXTRACTION:

Only studies reporting both the sensitivity and specificity of thallium scintigraphy were analyzed.

RESULTS:

Discriminant accuracy for diagnosis and prognosis was summarized in terms of pooled sensitivity and specificity.

CONCLUSIONS:

Exercise thallium scintigraphy is useful in the noninvasive diagnosis of coronary artery disease, especially in patients with abnormal resting electrocardiograms, restricted exercise tolerance, and intermediate probability of having disease at the time of testing as well as of defining the prognosis of patients with known or suspected coronary artery disease, especially in those with previous myocardial infarction. Because of various shortcomings in the published record, however, the marginal discriminant accuracy and cost effectiveness of thallium scintigraphy compared with conventional clinical assessment and exercise electrocardiography remain controversial.

PMID:
2221649
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Write to the Help Desk