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J Surg Oncol. 2012 May;105(6):617-21. doi: 10.1002/jso.22130. Epub 2012 Jan 3.

Updates on the multimodality management of desmoplastic small round cell tumor.

Author information

  • 1Department of Surgical Oncology, All India Institute of Medical Science, New Delhi, India. docash04@yahoo.com

Abstract

Desmoplastic Small Round Cell Tumor (DSRCT) is a rare and an aggressive malignancy with poor outcome. This tumor can co-express epithelial, neural, and mesenchymal markers. The molecular hallmark of DSRCT is the EWS-WT1 fusion protein. Despite the diversities in treatment modality, the best results have been seen with radical surgery and adjuvant or neoadjuvant chemotherapy.

Copyright © 2011 Wiley Periodicals, Inc.

PMID:
22215508
[PubMed - indexed for MEDLINE]
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