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    Results: 1 to 20 of 25

    1.

    Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover.

    Unger RH, Cherrington AD.

    J Clin Invest. 2012 Jan 3;122(1):4-12. doi: 10.1172/JCI60016. Epub 2012 Jan 3. Review.

    PMID:
    22214853
    [PubMed - indexed for MEDLINE]
    Free Article

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    2.

    Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes.

    Ziolkowski AF, Popp SK, Freeman C, Parish CR, Simeonovic CJ.

    J Clin Invest. 2012 Jan 3;122(1):132-41. doi: 10.1172/JCI46177. Epub 2011 Dec 19.

    PMID:
    22182841
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    3.

    Intravital imaging of CTLs killing islet cells in diabetic mice.

    Coppieters K, Amirian N, von Herrath M.

    J Clin Invest. 2012 Jan 3;122(1):119-31. doi: 10.1172/JCI59285. Epub 2011 Dec 1.

    PMID:
    22133877
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    4.

    Connexins protect mouse pancreatic β cells against apoptosis.

    Klee P, Allagnat F, Pontes H, Cederroth M, Charollais A, Caille D, Britan A, Haefliger JA, Meda P.

    J Clin Invest. 2011 Dec;121(12):4870-9. doi: 10.1172/JCI40509. Epub 2011 Nov 7.

    PMID:
    22056383
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    5.

    Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane.

    Tang WH, Stitham J, Gleim S, Di Febbo C, Porreca E, Fava C, Tacconelli S, Capone M, Evangelista V, Levantesi G, Wen L, Martin K, Minuz P, Rade J, Patrignani P, Hwa J.

    J Clin Invest. 2011 Nov;121(11):4462-76. doi: 10.1172/JCI59291. Epub 2011 Oct 17.

    PMID:
    22005299
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    6.

    Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.

    Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM.

    J Clin Invest. 2011 Nov;121(11):4281-8. doi: 10.1172/JCI58554. Epub 2011 Oct 10.

    PMID:
    21985785
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    7.

    A fragment of secreted Hsp90α carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice.

    Cheng CF, Sahu D, Tsen F, Zhao Z, Fan J, Kim R, Wang X, O'Brien K, Li Y, Kuang Y, Chen M, Woodley DT, Li W.

    J Clin Invest. 2011 Nov;121(11):4348-61. doi: 10.1172/JCI46475. Epub 2011 Oct 24. Erratum in: J Clin Invest. 2012 Feb 1;122(2):779.

    PMID:
    22019588
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    8.

    Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.

    Liu SM, Lee DH, Sullivan JM, Chung D, Jäger A, Shum BO, Sarvetnick NE, Anderson AC, Kuchroo VK.

    J Clin Invest. 2011 Nov;121(11):4303-10. doi: 10.1172/JCI46187. Epub 2011 Oct 24.

    PMID:
    22019586
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    9.

    Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice.

    Wei FY, Suzuki T, Watanabe S, Kimura S, Kaitsuka T, Fujimura A, Matsui H, Atta M, Michiue H, Fontecave M, Yamagata K, Suzuki T, Tomizawa K.

    J Clin Invest. 2011 Sep;121(9):3598-608. doi: 10.1172/JCI58056. Epub 2011 Aug 15.

    PMID:
    21841312
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    10.

    Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes.

    Tiano JP, Delghingaro-Augusto V, Le May C, Liu S, Kaw MK, Khuder SS, Latour MG, Bhatt SA, Korach KS, Najjar SM, Prentki M, Mauvais-Jarvis F.

    J Clin Invest. 2011 Aug;121(8):3331-42. doi: 10.1172/JCI44564. Epub 2011 Jul 11.

    PMID:
    21747171
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    11.

    Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets.

    Montane J, Bischoff L, Soukhatcheva G, Dai DL, Hardenberg G, Levings MK, Orban PC, Kieffer TJ, Tan R, Verchere CB.

    J Clin Invest. 2011 Aug;121(8):3024-8.

    PMID:
    21737880
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    12.

    Dynamics of insulin secretion and the clinical implications for obesity and diabetes.

    Seino S, Shibasaki T, Minami K.

    J Clin Invest. 2011 Jun;121(6):2118-25. doi: 10.1172/JCI45680. Epub 2011 Jun 1. Review.

    PMID:
    21633180
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    13.

    Circadian rhythms, sleep, and metabolism.

    Huang W, Ramsey KM, Marcheva B, Bass J.

    J Clin Invest. 2011 Jun;121(6):2133-41. doi: 10.1172/JCI46043. Epub 2011 Jun 1. Review.

    PMID:
    21633182
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    14.

    The role of lipid droplets in metabolic disease in rodents and humans.

    Greenberg AS, Coleman RA, Kraemer FB, McManaman JL, Obin MS, Puri V, Yan QW, Miyoshi H, Mashek DG.

    J Clin Invest. 2011 Jun;121(6):2102-10. doi: 10.1172/JCI46069. Epub 2011 Jun 1. Review.

    PMID:
    21633178
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    15.

    mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.

    Inoki K, Mori H, Wang J, Suzuki T, Hong S, Yoshida S, Blattner SM, Ikenoue T, Rüegg MA, Hall MN, Kwiatkowski DJ, Rastaldi MP, Huber TB, Kretzler M, Holzman LB, Wiggins RC, Guan KL.

    J Clin Invest. 2011 Jun;121(6):2181-96. doi: 10.1172/JCI44771. Epub 2011 May 23.

    PMID:
    21606597
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    16.

    Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.

    Gödel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S, Debreczeni-Mór A, Lindenmeyer MT, Rastaldi MP, Hartleben G, Wiech T, Fornoni A, Nelson RG, Kretzler M, Wanke R, Pavenstädt H, Kerjaschki D, Cohen CD, Hall MN, Rüegg MA, Inoki K, Walz G, Huber TB.

    J Clin Invest. 2011 Jun;121(6):2197-209. doi: 10.1172/JCI44774. Epub 2011 May 23.

    PMID:
    21606591
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    17.

    Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice.

    Viret C, Leung-Theung-Long S, Serre L, Lamare C, Vignali DA, Malissen B, Carrier A, Guerder S.

    J Clin Invest. 2011 May;121(5):1810-21. doi: 10.1172/JCI43314. Epub 2011 Apr 18.

    PMID:
    21505262
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    18.

    RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice.

    McCartney SA, Vermi W, Lonardi S, Rossini C, Otero K, Calderon B, Gilfillan S, Diamond MS, Unanue ER, Colonna M.

    J Clin Invest. 2011 Apr;121(4):1497-507. doi: 10.1172/JCI44005. Epub 2011 Mar 14.

    PMID:
    21403398
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    19.

    Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.

    Rhee EP, Cheng S, Larson MG, Walford GA, Lewis GD, McCabe E, Yang E, Farrell L, Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, Gerszten RE.

    J Clin Invest. 2011 Apr;121(4):1402-11. doi: 10.1172/JCI44442. Epub 2011 Mar 14.

    PMID:
    21403394
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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    20.

    α3(V) collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues.

    Huang G, Ge G, Wang D, Gopalakrishnan B, Butz DH, Colman RJ, Nagy A, Greenspan DS.

    J Clin Invest. 2011 Feb;121(2):769-83.

    PMID:
    21293061
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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