VarSifter: visualizing and analyzing exome-scale sequence variation data on a desktop computer

Bioinformatics. 2012 Feb 15;28(4):599-600. doi: 10.1093/bioinformatics/btr711. Epub 2011 Dec 30.

Abstract

VarSifter is a graphical software tool for desktop computers that allows investigators of varying computational skills to easily and quickly sort, filter, and sift through sequence variation data. A variety of filters and a custom query framework allow filtering based on any combination of sample and annotation information. By simplifying visualization and analyses of exome-scale sequence variation data, this program will help bring the power and promise of massively-parallel DNA sequencing to a broader group of researchers.

Availability and implementation: VarSifter is written in Java, and is freely available in source and binary versions, along with a User Guide, at http://research.nhgri.nih.gov/software/VarSifter/.

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Computational Biology / methods*
  • Exome*
  • High-Throughput Nucleotide Sequencing / methods*
  • Software*