Rev Med Interne. 2012 Feb;33(2):87-93. doi: 10.1016/j.revmed.2011.11.010. Epub 2011 Dec 28.

[Vitamin D and autoimmunity. Second part: Clinical aspects].

[Article in French]

Schoindre Y, Terrier B, Kahn JE, Saadoun D, Souberbielle JC, Benveniste O, Amoura Z, Piette JC, Cacoub P, Costedoat-Chalumeau N.

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Service de médecine interne, université Versailles-Saint-Quentin-en-Yvelines, hôpital Foch, 40, rue Worth, 92151 Suresnes cedex, France. y.schoindre@hopital-foch.org

Abstract

Vitamin D is often confined to its role in calcium homeostasis and bone metabolism. An exponential literature discusses its non-skeletal effects, especially its central role in the physiology of the immune system, where it acts at several levels to maintain self-tolerance. Here, the authors review the experimental, epidemiological and clinical studies, illustrating the potential role of vitamin D in the development and perpetuation of autoimmune diseases such as systemic lupus erythematosus, type 1 diabetes mellitus, multiple sclerosis, inflammatory bowel diseases or rheumatoid arthritis.

Comment in

[Sun and rheumatoid arthritis]. [Rev Med Interne. 2012]
[Sun and rheumatoid arthritis].Thomas M. Rev Med Interne. 2012 Jun; 33(6):351. Epub 2012 May 8.

PMID:: 22209319; [PubMed - indexed for MEDLINE]

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[Vitamin D and autoimmunity. Second part: Clinical aspects].
[Vitamin D and autoimmunity. Second part: Clinical aspects].
Rev Med Interne. 2012 Feb ;33(2):87-93. doi: 10.1016/j.revmed.2011.11.010. Epub 2011 Dec 28 .

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