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Nutr J. 2011 Dec 29;10:140. doi: 10.1186/1475-2891-10-140.

The effects of varying protein and energy intakes on the growth and body composition of very low birth weight infants.

Author information

  • 1Neonatal Unit, Hospital ClĂ­nic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.

Abstract

OBJECTIVE:

To determine the effects of high dietary protein and energy intake on the growth and body composition of very low birth weight (VLBW) infants.

STUDY DESIGN:

Thirty-eight VLBW infants whose weights were appropriate for their gestational ages were assessed for when they could tolerate oral intake for all their nutritional needs. Thirty-two infants were included in a longitudinal, randomized clinical trial over an approximate 28-day period. One control diet (standard preterm formula, group A, n = 8, 3.7 g/kg/d of protein and 129 kcal/kg/d) and two high-energy and high-protein diets (group B, n = 12, 4.2 g/kg/d and 150 kcal/kg/d; group C, n = 12, 4.7 g/kg/d and 150 kcal/kg/d) were compared. Differences among groups in anthropometry and body composition (measured with bioelectrical impedance analysis) were determined. An enriched breast milk group (n = 6) served as a descriptive reference group.

RESULTS:

Groups B and C displayed greater weight gains and higher increases in fat-free mass than group A.

CONCLUSION:

An intake of 150 kcal/kg/d of energy and 4.2 g/kg/d of protein increases fat-free mass accretion in VLBW infants.

PMID:
22206271
[PubMed - indexed for MEDLINE]
PMCID:
PMC3265432
Free PMC Article
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