Send to:

Choose Destination
See comment in PubMed Commons below
Nutr J. 2011 Dec 29;10:140. doi: 10.1186/1475-2891-10-140.

The effects of varying protein and energy intakes on the growth and body composition of very low birth weight infants.

Author information

  • 1Neonatal Unit, Hospital ClĂ­nic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.



To determine the effects of high dietary protein and energy intake on the growth and body composition of very low birth weight (VLBW) infants.


Thirty-eight VLBW infants whose weights were appropriate for their gestational ages were assessed for when they could tolerate oral intake for all their nutritional needs. Thirty-two infants were included in a longitudinal, randomized clinical trial over an approximate 28-day period. One control diet (standard preterm formula, group A, n = 8, 3.7 g/kg/d of protein and 129 kcal/kg/d) and two high-energy and high-protein diets (group B, n = 12, 4.2 g/kg/d and 150 kcal/kg/d; group C, n = 12, 4.7 g/kg/d and 150 kcal/kg/d) were compared. Differences among groups in anthropometry and body composition (measured with bioelectrical impedance analysis) were determined. An enriched breast milk group (n = 6) served as a descriptive reference group.


Groups B and C displayed greater weight gains and higher increases in fat-free mass than group A.


An intake of 150 kcal/kg/d of energy and 4.2 g/kg/d of protein increases fat-free mass accretion in VLBW infants.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Write to the Help Desk