Evaluation of preoperative computed tomography in estimating peritoneal cancer index in peritoneal carcinomatosis

Gan To Kagaku Ryoho. 2011 Nov;38(12):2060-4.

Abstract

Purpose: To evaluate the utility of CT of peritoneal carcinomatosis (PC) by comparing preoperative radiological and intraoperative peritoneal cancer index (PCI) scores.

Material and method: This study collected 76 patients of PC from different disease origins. The sensitivity, specificity and accuracy were calculated in each of the abdominopelvic region, and by tumor histologic type.

Result: An overall sensitivity of CT was 69%. The detection rate was highest in appendix and lowest in stomach group( 84% and 47%, respectively) by the origin of primary disease. There was a lower detection rate (59% vs 79%, p=0.001), and a higher underestimation rate (29% vs 21%, p<0.05) of small bowel lesion compared with overall abdomino-pelvic region. CT predicted an individual regional PCI score accurately in 65%, underestimated in 24%, and overestimated in 11%. CT detection rate in small tumor (<0.5 cm) was 29%, and increased to 97% with nodules size exceeding 5 cm. CT significantly underestimated the clinical PCI value in overall.

Conclusion: The sensitivity of CT in detecting PC was influenced by histologic type, tumor location and size. CT underestimated the clinical PCI score in PC patient.

MeSH terms

  • Adult
  • Aged
  • Carcinoma / diagnostic imaging*
  • Carcinoma / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Peritoneal Neoplasms / diagnostic imaging*
  • Peritoneal Neoplasms / surgery
  • Tomography, X-Ray Computed / methods*