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J Maxillofac Oral Surg. 2010 Dec;9(4):389-95. doi: 10.1007/s12663-010-0132-6. Epub 2011 Mar 11.

Epidemiological Analysis of Cleft Lip and/or Palate by Cleft Pattern.

Abstract

OBJECTIVES:

To analyze gender differences in cleft pattern by the clinical statistical study of Japanese patients with cleft lip and/or cleft palate.

STUDY DESIGN:

Cleft pattern modeling was used to analyze 782 patients with cleft lip and/or cleft palate (417 males and 365 females) who had been examined at the Cleft Lip and Palate Center, Aichi-Gakuin University Hospital, and whose details could be confirmed. Relationships between gender and cleft type were analyzed with chi-squared test.

RESULTS:

A comparison of gender differences by cleft type revealed that a greater percentage of males had milder cleft lip, cleft lip and palate, or cleft palate, whereas the percentage of females tended to be greater as cleft severity increased.

CONCLUSIONS:

Modeling of cleft patterns enables more detailed classification of cleft lip and palate, and can lead to a greater understanding of pathology.

KEYWORDS:

Cleft lip; Cleft palate; Clinical statistics; Congenital malformation

PMID:
22190831
[PubMed]
PMCID:
PMC3177484
Free PMC Article
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