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J Clin Microbiol. 2012 Mar;50(3):1039-42. doi: 10.1128/JCM.06438-11. Epub 2011 Dec 21.

Oral streptococcal bacteremia in hospitalized patients: taxonomic identification and clinical characterization.

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  • 1The Philips Institute of Oral and Craniofacial Molecular Biology, Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, USA.


Oral streptococci have been associated with systemic diseases, including infective endocarditis and neutropenic bacteremia. We analyzed 58 recent oral streptococcal bloodstream isolates, and we obtained clinical and demographic data for source patients. The sodA gene was found to be a better target than the 16S-23S rRNA internal transcribed spacer for DNA sequence-based species identification. Together, Streptococcus mitis and Streptococcus oralis were significantly more likely than the 12 combined remaining species to be isolated from neutropenic patients.

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