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Vaccine. 2011 Dec 30;29 Suppl 4:D60-4. doi: 10.1016/j.vaccine.2011.09.004. Epub 2011 Dec 19.

Whither monkeypox vaccination.

Author information

  • 1University of California, Los Angeles School of Public Health, Los Angeles, CA, USA.

Abstract

Monkeypox (MPX) is a virulent orthopoxvirus that is endemic in some regions of Central Africa. MPX incidence has been rising since the cessation of routine smallpox immunization. While it causes significant disease, there is limited person-to-person spread, the incidence is still relatively low, and cases are generally restricted to remote areas that are difficult to access. Therefore, initiating vaccine trials or implementing vaccination programs would be challenging. This paper considers the factors that may influence future decisions on whether MPX vaccination should be pursued.

Published by Elsevier Ltd.

KEYWORDS:

Orthopoxvirus; biodefense; smallpox; vaccine; variola

PMID:
22188935
[PubMed - indexed for MEDLINE]
PMCID:
PMC3311705
Free PMC Article
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