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HIV Clin Trials. 2011 Sep-Oct;12(5):275-6. doi: 10.1310/hct1205-275.

Vitamin D supplementation does not increase immunogenicity of seasonal influenza vaccine in HIV-infected adults.

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  • 1The Ottawa Hospital Division of Infectious Diseases, University of Ottawa, Ottawa, Canada. ccooper@ottawahospital.on.ca

Abstract

The influence of vitamin D on influenza vaccine immunogenicity in HIV was assessed using data from a phase 3, randomized trial conducted during the 2008-2009 influ-enza season. Thirty-three percent of participants were on supplemental vitamin D at baseline. Neither seroconversion nor seroprotection were predicted by vitamin D use for any of the 3 vaccine strains. There is no evidence of improved influenza vaccine immunogenicity with vitamin D supplementation in this HIV-positive population.

PMID:
22180525
[PubMed - indexed for MEDLINE]
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