[Community-acquired methicillin-resistant Staphylococcus aureus: Review]

Presse Med. 2012 Jul;41(7-8):713-20. doi: 10.1016/j.lpm.2011.10.022. Epub 2011 Dec 16.
[Article in French]

Abstract

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have emerged worldwide. These CA-MRSA are different from classical hospital-acquired MRSA. They share common characteristics: they affect mainly young subjects, without past medical history. The majority of strains produce the Panton-Valentine leukocidin. They are mainly responsible for suppurative skin infections and rarely for invasive infections such as necrotizing pneumonia. The situation in the US is alarming with a main circulating clone the USA300 clone, whereas in Europe, the diffusion of CA-MRSA strains remains limited. It is important to take advantage of the experience acquired from the US to limit the potential spread of such CA-MRSA strains.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Community-Acquired Infections / epidemiology*
  • Community-Acquired Infections / etiology
  • Community-Acquired Infections / therapy
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • Cross Infection / therapy
  • Europe / epidemiology
  • France / epidemiology
  • Humans
  • Methicillin Resistance / genetics
  • Methicillin Resistance / physiology
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Methicillin-Resistant Staphylococcus aureus / metabolism
  • Methicillin-Resistant Staphylococcus aureus / pathogenicity
  • Methicillin-Resistant Staphylococcus aureus / physiology*
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / therapy
  • United States / epidemiology
  • Virulence Factors / genetics

Substances

  • Virulence Factors