Int J STD AIDS. 2011 Dec;22(12):695-708. doi: 10.1258/ijsa.2011.171011.

UK guideline for the use of post-exposure prophylaxis for HIV following sexual exposure (2011).

Benn P, Fisher M, Kulasegaram R; BASHH; PEPSE Guidelines Writing Group Clinical Effectiveness Group.

Collaborators (15)

Azad Y, Delpech V, Fox J, Hardie J, Hawkins D, Hedge B, Radcliffe K, Richardson C, Taylor S, Daniels D, FitzGerald M, Kingston M, Lazaro N, McCarthy G, Sullivan A.

Source

Camden Provider Services, Central and North West London NHS Foundation Trust, London. paul.benn@nhs.net

Abstract

We present the updated British Association for Sexual Health and HIV (BASHH) guidelines for post-exposure prophylaxis (PEPSE) to HIV. This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provides recommendations on when PEPSE would and would not be considered. We review which agents to use for PEPSE including the potential for drug-drug interactions and make recommendations for monitoring individuals receiving PEPSE. Other areas included are the possible impact on sexual behaviour, cost-effectiveness and issues relating to service provision. Throughout the document, consideration is given to the place of PEPSE within the broader context of HIV prevention strategies and sexual health.