Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Am J Surg. 2012 Jun;203(6):708-14. doi: 10.1016/j.amjsurg.2011.06.051. Epub 2011 Dec 6.

Preventing seroma formation after axillary dissection for breast cancer: a randomized clinical trial.

Author information

  • 1Department of Surgery, Second University of Naples, Piazza Miraglia 1, 80138 Naples, Italy. francesco.iovino@unina2.it

Abstract

BACKGROUND:

Seroma formation after axillary dissection remains the most common early sequel to breast cancer surgery. Different surgical approaches have been performed to reduce seroma collection. Therefore, we aimed to assess the outcome of patients operated on using an ultrasound scalpel according to a standardized operative technique before accepting it as a routine procedure.

METHODS:

A randomized controlled trial was designed to compare the outcome of patients undergoing breast surgery and axillary dissection using either standard scalpel blades, scissors, ligations, and electrocautery or the ultrasound scalpel only. Each arm of the trial consisted of 30 patients.

RESULTS:

A statistically significant benefit in terms of axillary and chest wall drainage volume, the number of axilla seromas, intraoperative bleeding, and hospitalization stay was recorded in the harmonic scalpel group. No significant differences were found between the 2 groups in terms of operative time. Finally, no postoperative hematoma, wound infections, and chest wall seroma were observed.

CONCLUSIONS:

The use of the harmonic scalpel was shown to reduce the magnitude of seromas in axilla and hospitalization stay. The harmonic scalpel can be used alone in axillary dissection with a safe and effective hemostasis. Our results must be confirmed by larger series.

Copyright © 2012 Elsevier Inc. All rights reserved.

Comment in

PMID:
22153087
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk