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Results: 12

1.

Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).

Blaser A, Palmer BD, Sutherland HS, Kmentova I, Franzblau SG, Wan B, Wang Y, Ma Z, Thompson AM, Denny WA.

J Med Chem. 2012 Jan 12;55(1):312-26. Epub 2011 Dec 29.

PMID:: 22148391; [PubMed - indexed for MEDLINE]

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2.

Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA and PtpB).

Chiaradia LD, Martins PG, Cordeiro MN, Guido RV, Ecco G, Andricopulo AD, Yunes RA, Vernal J, Nunes RJ, Terenzi H.

J Med Chem. 2012 Jan 12;55(1):390-402. Epub 2011 Dec 20.

PMID:: 22136336; [PubMed - indexed for MEDLINE]

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3.

Error occurred: cannot get document summary

PMID:: 22059810

4.

Current status and research strategies in tuberculosis drug development.

Dover LG, Coxon GD.

J Med Chem. 2011 Sep 22;54(18):6157-65. Epub 2011 Aug 16. Review. No abstract available. Erratum in: J Med Chem. 2011 Dec 8;54(23):8233.

PMID:: 21823589; [PubMed - indexed for MEDLINE]

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5.

A prodrug approach for improving antituberculosis activity of potent Mycobacterium tuberculosis type II dehydroquinase inhibitors.

Tizón L, Otero JM, Prazeres VF, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Ainsa JA, Castedo L, González-Bello C.

J Med Chem. 2011 Sep 8;54(17):6063-84. Epub 2011 Aug 3.

PMID:: 21780742; [PubMed - indexed for MEDLINE]

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6.

Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain.

Boechat N, Ferreira VF, Ferreira SB, de Lourdes G Ferreira M, de C da Silva F, Bastos MM, Dos S Costa M, Lourenço MC, Pinto AC, Krettli AU, Aguiar AC, Teixeira BM, da Silva NV, Martins PR, Bezerra FA, Camilo AL, da Silva GP, Costa CC.

J Med Chem. 2011 Sep 8;54(17):5988-99. Epub 2011 Aug 15.

PMID:: 21776985; [PubMed - indexed for MEDLINE]

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7.

Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase.

Andaloussi M, Henriksson LM, Więckowska A, Lindh M, Björkelid C, Larsson AM, Suresh S, Iyer H, Srinivasa BR, Bergfors T, Unge T, Mowbray SL, Larhed M, Jones TA, Karlén A.

J Med Chem. 2011 Jul 28;54(14):4964-76. Epub 2011 Jul 1.

PMID:: 21678907; [PubMed - indexed for MEDLINE]

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8.

Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis.

Kögler M, Vanderhoydonck B, De Jonghe S, Rozenski J, Van Belle K, Herman J, Louat T, Parchina A, Sibley C, Lescrinier E, Herdewijn P.

J Med Chem. 2011 Jul 14;54(13):4847-62. Epub 2011 Jun 9.

PMID:: 21657202; [PubMed - indexed for MEDLINE]

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9.

Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA).

Kim HY, Wiles JA, Wang Q, Pais GC, Lucien E, Hashimoto A, Nelson DM, Thanassi JA, Podos SD, Deshpande M, Pucci MJ, Bradbury BJ.

J Med Chem. 2011 May 12;54(9):3268-82. Epub 2011 Apr 15.

PMID:: 21425851; [PubMed - indexed for MEDLINE]

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10.

ATP-binding site of bacterial enzymes as a target for antibacterial drug design.

Škedelj V, Tomašić T, Mašič LP, Zega A.

J Med Chem. 2011 Feb 24;54(4):915-29. Epub 2011 Jan 14. Review. No abstract available.

PMID:: 21235241; [PubMed - indexed for MEDLINE]

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11.

Error occurred: cannot get document summary

PMID:: 21306109

12.

FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation.

Klein T, Abgottspon D, Wittwer M, Rabbani S, Herold J, Jiang X, Kleeb S, Lüthi C, Scharenberg M, Bezençon J, Gubler E, Pang L, Smiesko M, Cutting B, Schwardt O, Ernst B.

J Med Chem. 2010 Dec 23;53(24):8627-41. Epub 2010 Nov 24.

PMID:: 21105658; [PubMed - indexed for MEDLINE]

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Structure-activity relationships for amide-, carbamate-, and urea-linked analogu...
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
J Med Chem. 2012 Jan 12 ;55(1):312-26. Epub 2011 Dec 29 .

PubMed
Prediction of risk in noncardiac operations after cardiac operations.
Prediction of risk in noncardiac operations after cardiac operations.
J Thorac Cardiovasc Surg. 1990 Oct ;100(4):595-605.

PubMed
Searching for DNA lesions: structural evidence for lower- and higher-affinity DN...
Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase.
Biochemistry. 2012 Jan 10 ;51(1):382-90. Epub 2011 Dec 20 .

PubMed
[Internet addictive behaviour].
[Internet addictive behaviour].
Zh Nevrol Psikhiatr Im S S Korsakova. 2011 ;111(8 Pt 1):86-92.

PubMed
A model of stem cell population dynamics: in silico analysis and in vivo validat...
A model of stem cell population dynamics: in silico analysis and in vivo validation.
Development. 2012 Jan ;139(1):47-56.

PubMed

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