Science. 2011 Dec 2;334(6060):1230-2. doi: 10.1126/science.1211811.

Improving validation practices in "omics" research.

Source

Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

"Omics" research poses acute challenges regarding how to enhance validation practices and eventually the utility of this rich information. Several strategies may be useful, including routine replication, public data and protocol availability, funding incentives, reproducibility rewards or penalties, and targeted repeatability checks.

PMID:: 22144616; [PubMed - indexed for MEDLINE]

MeSH Terms

LinkOut - more resources

Full Text Sources

Miscellaneous

See the articles recommended by F1000Prime's Faculty of 5,000 renowned researchers and clinicians, assisted by 5,000 associates. - F1000

Supplemental Content

Save items

Related citations in PubMed

What can metabolomics learn from genomics and proteomics? [Curr Opin Biotechnol. 2009]
What can metabolomics learn from genomics and proteomics?
Arita M. Curr Opin Biotechnol. 2009 Dec; 20(6):610-5. Epub 2009 Oct 21.
A plea for "omics" research in complex diseases such as multiple sclerosis--a change of mind is needed. [J Neurol Sci. 2004]
A plea for "omics" research in complex diseases such as multiple sclerosis--a change of mind is needed.
Martin R, Leppert D. J Neurol Sci. 2004 Jul 15; 222(1-2):3-5.
Review Integrating multiple 'omics' analysis for microbial biology: application and methodologies. [Microbiology. 2010]
Review Integrating multiple 'omics' analysis for microbial biology: application and methodologies.
Zhang W, Li F, Nie L. Microbiology. 2010 Feb; 156(Pt 2):287-301. Epub 2009 Nov 12.
Review Progress in standards for reporting omics data. [Curr Opin Drug Discov Devel. 2...]
Review Progress in standards for reporting omics data.
Taylor CF. Curr Opin Drug Discov Devel. 2007 May; 10(3):254-63.
Review Data publishing and scientific journals: the future of the scientific paper in a world of shared data. [Neuroinformatics. 2010]
Review Data publishing and scientific journals: the future of the scientific paper in a world of shared data.
De Schutter E. Neuroinformatics. 2010 Oct; 8(3):151-3.

See reviews... See all...

Cited by 7 PubMed Central articles

Access to chemical data: Lutter et al. respond. [Environ Health Perspect. 2013]
Access to chemical data: Lutter et al. respond.
Lutter R, Barrow C, Borgert CJ Jr, Conrad JW, Edwards D, Felsot A. Environ Health Perspect. 2013 Apr; 121(4):A112.
G-cimp status prediction of glioblastoma samples using mRNA expression data. [PLoS One. 2012]
G-cimp status prediction of glioblastoma samples using mRNA expression data.
Baysan M, Bozdag S, Cam MC, Kotliarova S, Ahn S, Walling J, Killian JK, Stevenson H, Meltzer P, Fine HA. PLoS One. 2012; 7(11):e47839. Epub 2012 Nov 6.
Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data. [PLoS One. 2012]
Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data.
Huber-Keener KJ, Liu X, Wang Z, Wang Y, Freeman W, Wu S, Planas-Silva MD, Ren X, Cheng Y, Zhang Y, et al. PLoS One. 2012; 7(7):e41333. Epub 2012 Jul 23.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Improving validation practices in "omics" research.
Improving validation practices in "omics" research.
Science. 2011 Dec 2 ;334(6060):1230-2. doi: 10.1126/science.1211811.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Improving validation practices in "omics" research.

Source

Abstract

MeSH Terms

MeSH Terms

LinkOut - more resources

Full Text Sources

Miscellaneous

Supplemental Content

Save items

Related citations in PubMed

Cited by 7 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information