Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Pain Res Treat. 2012;2012:184835. doi: 10.1155/2012/184835. Epub 2011 Oct 29.

The clinical concept of fibromyalgia as a changing paradigm in the past 20 years.

Author information

  • 1Division of Rheumatology, McGill University, Montreal, QC, Canada H3G 1A4.

Abstract

Fibromyalgia (FMS) is a valid clinical condition that affects 2%-4% of the population with a pivot symptom of widespread body pain. The cause and cure of FMS are as yet unknown. The concept of FMS has evolved over the past two decades to incorporate symptoms beyond pain as contributing to the global spectrum of suffering. FMS is now recognized to be grounded in the neurological domain with evidence of dysregulation of pain processing. Appreciation of the neurophysiologic mechanisms operative in FMS has contributed to rational treatment recommendations, although a "gold standard treatment" does not currently exist. Ideal treatments for FMS patients should be individualized with emphasis on active patient participation, good health practices, and multimodal intervention, incorporating nonpharmacologic and pharmacologic treatments. Predictors of outcome, which is favourable in over 50% of patients, are unknown, but those with better outcome do more physical activity and use fewer medications.

PMID:
22135738
[PubMed]
PMCID:
PMC3205680
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk