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    J Acquir Immune Defic Syndr. 1990;3(11):1023-40.

    Immunologic and pathologic manifestations of the infection of rhesus monkeys with simian immunodeficiency virus of macaques.

    Source

    Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts 01772.

    Abstract

    The striking similarities between simian immunodeficiency virus (SIV)-induced disease in macaque monkeys and HIV-induced disease in humans make the SIV-induced macaque monkey an extraordinarily important model for the study of AIDS. The most significant difference between these lentivirus-induced syndromes is the more rapid progression of disease in SIV-infected monkeys. The immunologic and pathologic manifestations of SIV infections in rhesus monkeys are described.

    PMID:
    2213505
    [PubMed - indexed for MEDLINE]

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