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Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208031, 300 Cedar St., New Haven, CT 06520-8031, USA. stephen.malawista@yale.edu
This is a discussion of acute gouty arthritis, seen for over 50 years of engagement. It addresses the evolution of our current understanding of the interaction between urate crystals and key cellular components of the gouty inflammatory paroxysm, with new material on pathogenesis.
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