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Best Pract Res Clin Haematol. 2011 Dec;24(4):505-8. doi: 10.1016/j.beha.2011.09.005.

Flow cytometry in the post fluorescence era.

Author information

  • Stanford University School of Medicine, CA 94305, USA. gnolan@standford.edu

Abstract

While flow cytometry once enabled researchers to examine 10--15 cell surface parameters, new mass flow cytometry technology enables interrogation of up to 45 parameters on a single cell. This new technology has increased understanding of cell expression and how cells differentiate during hematopoiesis. Using this information, knowledge of leukemia cell biology has also increased. Other new technologies, such as SPADE analysis and single cell network profiling (SCNP), are enabling researchers to put different cancers into more biologically similar categories and have the potential to enable more personalized medicine.

Copyright © 2011. Published by Elsevier Ltd.

PMID:
22127312
[PubMed - indexed for MEDLINE]
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