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    J Bacteriol. 2011 Dec;193(24):7005.

    Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10.

    Source

    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy Medical Sciences & Peking Union Medical College, Beijing 100176, China.

    Abstract

    Neonatal bacterial meningitis continues to be an important cause of mortality and morbidity worldwide. Escherichia coli possessing the K1 capsular polysaccharide is the most common Gram-negative pathogen causing neonatal meningitis. Here we present the complete genome sequence of neonatal meningitis-associated E. coli strain CE10, a unique K1 strain with a functional type III secretion system. Functional analysis of the genome should enhance our knowledge of the pathogenesis of neonatal E. coli K1 meningitis.

    PMID:
    22123760
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC3232859
    Free full text

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