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J Bacteriol. 2011 Dec;193(24):6995-6. doi: 10.1128/JB.05951-11.

Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates.

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  • 1Department of Pathology, Division of Microbiology and Immunology, University of Utah Medical School, Salt Lake City, Utah 84112, USA.


Human Lyme disease is commonly caused by several species of spirochetes in the Borrelia genus. In Eurasia these species are largely Borrelia afzelii, B. garinii, B. burgdorferi, and B. bavariensis sp. nov. Whole-genome sequencing is an excellent tool for investigating and understanding the influence of bacterial diversity on the pathogenesis and etiology of Lyme disease. We report here the whole-genome sequences of four isolates from two of the Borrelia species that cause human Lyme disease, B. afzelii isolates ACA-1 and PKo and B. garinii isolates PBr and Far04.

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