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Acta Paediatr. 2012 Apr;101(4):338-43. doi: 10.1111/j.1651-2227.2011.02539.x. Epub 2011 Dec 23.

Cardiac biomarkers in neonatal hypoxic ischaemia.

Author information

  • 1Neonatology, National Maternity Hospital, Dublin, Ireland. dsweetman@nmh.ie

Abstract

Following a perinatal hypoxic-ischaemic insult, term infants commonly develop cardiovascular dysfunction. Troponin-T, troponin-I and brain natriuretic peptide are sensitive indicators of myocardial compromise. The long-term effects of cardiovascular dysfunction on neurodevelopmental outcome following perinatal hypoxic ischaemia remain controversial. Follow-up studies are warranted to ensure optimal cardiac function in adulthood.

CONCLUSION:

Cardiac biomarkers may improve the diagnosis of myocardial injury, help guide management, estimate mortality risk and may also aid in longterm neurodevelopmental outcome prediction following neonatal hypoxic-ischaemia.

© 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

PMID:
22118561
[PubMed - indexed for MEDLINE]
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