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    Acta Paediatr. 2012 Apr;101(4):338-43. doi: 10.1111/j.1651-2227.2011.02539.x. Epub 2011 Dec 23.

    Cardiac biomarkers in neonatal hypoxic ischaemia.

    Sweetman D, Armstrong K, Murphy JF, Molloy EJ.

    Source

    Neonatology, National Maternity Hospital, Dublin, Ireland. dsweetman@nmh.ie

    Abstract

    Following a perinatal hypoxic-ischaemic insult, term infants commonly develop cardiovascular dysfunction. Troponin-T, troponin-I and brain natriuretic peptide are sensitive indicators of myocardial compromise. The long-term effects of cardiovascular dysfunction on neurodevelopmental outcome following perinatal hypoxic ischaemia remain controversial. Follow-up studies are warranted to ensure optimal cardiac function in adulthood. CONCLUSION: Cardiac biomarkers may improve the diagnosis of myocardial injury, help guide management, estimate mortality risk and may also aid in longterm neurodevelopmental outcome prediction following neonatal hypoxic-ischaemia.

    © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

    PMID:
    22118561
    [PubMed - in process]

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