Send to:

Choose Destination
See comment in PubMed Commons below
Methods Cell Biol. 2011;106:343-75. doi: 10.1016/B978-0-12-544172-8.00013-X.

The genetics and cell biology of fertilization.

Author information

  • 1Waksman Institute, Rutgers University, Department of Microbiology and Molecular Genetics, Piscataway, New Jersey, USA.


Although the general events surrounding fertilization in many species are well described, the molecular underpinnings of fertilization are still poorly understood. Caenorhabditis elegans has emerged as a powerful model system for addressing the molecular and cell biological mechanism of fertilization. A primary advantage is the ability to isolate and propagate mutants that effect gametes and no other cells. This chapter provides conceptual guidelines for the identification, maintenance, and experimental approaches for the study fertility mutants.

Copyright © 2011 Elsevier Inc. All rights reserved.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk