Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Genome Biol Evol. 2012;4(1):13-23. doi: 10.1093/gbe/evr124. Epub 2011 Nov 24.

Causes and consequences of genome expansion in fungi.

Author information

  • 1Department of Ecology and Evolutionary Biology, Yale University, USA. yogeshwar.kelkar@yale.edu

Abstract

Fungi display a large diversity in genome size and complexity, variation that is often considered to be adaptive. But because nonadaptive processes can also have important consequences on the features of genomes, we investigated the relationship of genetic drift and genome size in the phylum Ascomycota using multiple indicators of genetic drift. We detected a complex relationship between genetic drift and genome size in fungi: genetic drift is associated with genome expansion on broad evolutionary timescales, as hypothesized for other eukaryotes; but within subphyla over smaller timescales, the opposite trend is observed. Moreover, fungi and bacteria display similar patterns of genome degradation that are associated with initial effects of genetic drift. We conclude that changes in genome size within Ascomycota have occurred using two different routes: large-scale genome expansions are catalyzed by increasing drift as predicted by the mutation-hazard model of genome evolution and small-scale modifications in genome size are independent of drift.

PMID:
22117086
[PubMed - indexed for MEDLINE]
PMCID:
PMC3267396
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk