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J Clin Psychiatry. 1990 Sep;51(9):383-4.

Reversal of fluoxetine-induced anorgasmia by cyproheptadine in two patients.

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  • 1Erich Lindemann Mental Health Center, Boston, MA 02114.

Abstract

The authors report two cases of ejaculatory dysfunction induced by fluoxetine. Cyproheptadine, an antihistaminic and antiserotonergic drug, restored sexual function in each case. Possible mechanisms of fluoxetine-induced anorgasmia are presented and treatment options are reviewed.

PMID:
2211550
[PubMed - indexed for MEDLINE]
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