AJR Am J Roentgenol. 2011 Dec;197(6):W1060-6.

CT findings of response and recurrence, independent of change in tumor size, in colorectal liver metastasis treated with bevacizumab.

Boonsirikamchai P, Asran MA, Maru DM, Vauthey JN, Kaur H, Kopetz S, Loyer EM.

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Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, 77030, USA.

Abstract

OBJECTIVE: The purpose of this article is to provide a practical review of newly established morphologic tumor response criteria for hepatic colorectal metastasis treated with bevacizumab-containing chemotherapy and a description of the patterns of early recurrence. We also discuss the respective value of these criteria and the Response Evaluation Criteria in Solid Tumors (RECIST). CONCLUSION: RECIST alone are not sufficient to assess response after bevacizumab-containing chemotherapy for hepatic colorectal metastasis. The combined use of RECIST and morphologic criteria is mandatory for optimal evaluation in this population.

PMID:: 22109320; [PubMed - indexed for MEDLINE]

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