Send to:

Choose Destination
See comment in PubMed Commons below
J Acquir Immune Defic Syndr. 2012 Feb 1;59(2):149-54. doi: 10.1097/QAI.0b013e318240566b.

Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study.

Author information

  • 1Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA.



To compare neuropsychological scores in women infected with HIV, women infected with both HIV and hepatitis C, and uninfected subjects.


Some, but not all, studies have demonstrated that dual infection with Hepatitis C virus (HCV) and HIV has worse effects on cognition than infection with HIV alone.


The Women's Interagency HIV Study is an ongoing prospective study of the natural history of HIV in women where participants are reevaluated every 6 months. In a cross-sectional analysis, we evaluated the effects of active HIV and HCV infections on scores on symbol-digit modalities test, the Stroop interference test, and trails A and B after controlling for age, ethnicity, education, depression, liver disease, and current or past substance abuse.


Data were available for 1338 women-17.8 % had detectable hepatitis C virus and 67% were HIV seropositive. In fully adjusted general linear models, HCV viremia was not associated with scores on any of the cognitive tests.


In this large sample of women, active HCV infection was not associated with scores on a small battery of neuropsychological tests.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins Icon for PubMed Central
    Loading ...
    Write to the Help Desk