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Nanoscale. 2012 Mar 21;4(6):1856-70. doi: 10.1039/c1nr11143d. Epub 2011 Nov 21.

Developments in and practical guidelines for tip-enhanced Raman spectroscopy.

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  • 1ETH Zurich, Department of Chemistry and Applied Biosciences, Wolfgang-Pauli-Strasse 10, HCI E 329, 8093 Zurich, Switzerland.


This feature review provides an overview of the state-of the art and recent developments in tip-enhanced Raman spectroscopy (TERS), in-depth information about the different available types of instruments including their (dis-)advantages and capabilities as well as a short glance at a number of samples that have recently been investigated using TERS. Issues concerning the progression of TERS from point spectroscopy to an imaging technique are discussed, as well as problems arising from background and contamination signals. This review is concluded with a short TERS 'user guideline', trying to aid researchers new in the field to properly align and test their own TERS setups. Finally, a short outlook is given and some critical issues are raised that need to be solved by the community sooner or later, in order to promote TERS towards a 'push-button' operation.

This journal is © The Royal Society of Chemistry 2012

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