Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitination.
Bhatt P, d'Avout C, Kane NS, Borowiec JA, Saxena A.
FEBS J. 2012 Feb;279(3):370-83. doi: 10.1111/j.1742-4658.2011.08430.x. Epub 2011 Dec 19.
Related citations
Long isoform of ErbB3 binding protein, p48, mediates protein kinase B/Akt-dependent HDM2 stabilization and nuclear localization.
Kim CK, Lee SB, Nguyen TL, Lee KH, Um SH, Kim J, Ahn JY.
Exp Cell Res. 2012 Jan 15;318(2):136-43. Epub 2011 Sep 9.
Ret finger protein 2 enhances ionizing radiation-induced apoptosis via degradation of AKT and MDM2.
Joo HM, Kim JY, Jeong JB, Seong KM, Nam SY, Yang KH, Kim CS, Kim HS, Jeong M, An S, Jin YW.
Eur J Cell Biol. 2011 May;90(5):420-31. Epub 2011 Feb 17.
The nucleolar SUMO-specific protease SMT3IP1/SENP3 attenuates Mdm2-mediated p53 ubiquitination and degradation.
Nishida T, Yamada Y.
Biochem Biophys Res Commun. 2011 Mar 11;406(2):285-91. Epub 2011 Feb 18.
JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress.
Liu J, Chung HJ, Vogt M, Jin Y, Malide D, He L, Dundr M, Levens D.
EMBO J. 2011 Mar 2;30(5):846-58. Epub 2011 Feb 1.
GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest.
Meng L, Hsu JK, Tsai RY.
Oncogene. 2011 Apr 7;30(14):1716-26. Epub 2010 Dec 6.
S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response.
Lai KP, Leong WF, Chau JF, Jia D, Zeng L, Liu H, He L, Hao A, Zhang H, Meek D, Velagapudi C, Habib SL, Li B.
EMBO J. 2010 Sep 1;29(17):2994-3006. Epub 2010 Jul 23.
A newly identified Pirh2 substrate SCYL1-BP1 can bind to MDM2 and accelerate MDM2 self-ubiquitination.
Yan J, Zhang D, Di Y, Shi H, Rao H, Huo K.
FEBS Lett. 2010 Aug 4;584(15):3275-8. Epub 2010 Jun 23.
Mdm2 facilitates the association of p53 with the proteasome.
Kulikov R, Letienne J, Kaur M, Grossman SR, Arts J, Blattner C.
Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10038-43. Epub 2010 May 17.
The tumor suppressor UCHL1 forms a complex with p53/MDM2/ARF to promote p53 signaling and is frequently silenced in nasopharyngeal carcinoma.
Li L, Tao Q, Jin H, van Hasselt A, Poon FF, Wang X, Zeng MS, Jia WH, Zeng YX, Chan AT, Cao Y.
Clin Cancer Res. 2010 Jun 1;16(11):2949-58. Epub 2010 Apr 15.
Interplay between MDM2, MDMX, Pirh2 and COP1: the negative regulators of p53.
Wang L, He G, Zhang P, Wang X, Jiang M, Yu L.
Mol Biol Rep. 2011 Jan;38(1):229-36. Epub 2010 Mar 24.
MdmX is a substrate for the deubiquitinating enzyme USP2a.
Allende-Vega N, Sparks A, Lane DP, Saville MK.
Oncogene. 2010 Jan 21;29(3):432-41. Epub 2009 Oct 19.
Ribosomal protein S7 is both a regulator and a substrate of MDM2.
Zhu Y, Poyurovsky MV, Li Y, Biderman L, Stahl J, Jacq X, Prives C.
Mol Cell. 2009 Aug 14;35(3):316-26.
Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
Okamoto K, Taya Y, Nakagama H.
FEBS Lett. 2009 Sep 3;583(17):2710-4. Epub 2009 Jul 18.
Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells.
Lu TL, Huang GJ, Lu TJ, Wu JB, Wu CH, Yang TC, Iizuka A, Chen YF.
Food Chem Toxicol. 2009 Aug;47(8):2013-21. Epub 2009 May 27.
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathway.
Lee HR, Toth Z, Shin YC, Lee JS, Chang H, Gu W, Oh TK, Kim MH, Jung JU.
J Virol. 2009 Jul;83(13):6739-47. Epub 2009 Apr 15.
p14ARF interacts with DAXX: effects on HDM2 and p53.
Ivanchuk SM, Mondal S, Rutka JT.
Cell Cycle. 2008 Jun 15;7(12):1836-50. Epub 2008 Jun 30.
The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex.
Song MS, Song SJ, Kim SY, Oh HJ, Lim DS.
EMBO J. 2008 Jul 9;27(13):1863-74. Epub 2008 Jun 19.
CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2.
Yang W, Dicker DT, Chen J, El-Deiry WS.
Cell Cycle. 2008 Mar 1;7(5):670-82. Epub 2008 Jan 31.
The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA.
Cancer Cell. 2007 Oct;12(4):342-54.
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on