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Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitination.
Bhatt P, d'Avout C, Kane NS, Borowiec JA, Saxena A.
FEBS J. 2012 Feb;279(3):370-83. doi: 10.1111/j.1742-4658.2011.08430.x. Epub 2011 Dec 19.
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Nucleolin inhibits Hdm2 by multiple pathways leading to p53 stabilization.
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