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Cancer Cell. 2011 Nov 15;20(5):553-4. doi: 10.1016/j.ccr.2011.11.001.

Platelets alter tumor cell attributes to propel metastasis: programming in transit.

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  • 1The Scripps Research Institute, La Jolla, CA 92037, USA.


Metastasis of epithelial tumors critically depends on acquisition of a disseminating phenotype that allows tumor cells to colonize distant organs. In this issue of Cancer Cell, Labelle et al. demonstrate that an epithelial-mesenchymal-like transition can be induced by interaction between platelets and tumor cells.

2011 Elsevier Inc. All rights reserved.

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