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J Cytol. 2011 Oct;28(4):219-22. doi: 10.4103/0970-9371.86357.

Intraoperative cytology of central neurocytoma mimicking oligodendroglioma.

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  • 1Department of Pathology, Armed Forces Medical College, Pune, India.


Central neurocytomas (CNs) are uncommon tumors of the central nervous system. These tumors have a predilection for the lateral ventricles of young adults and are known to display characteristic neuroimaging and histomorphologic features. Typically, CNs are associated with a favorable outcome, although cases with more aggressive clinical course with recurrences are not unknown. Most descriptions of this tumor are available in the form of isolated histopathology-based case reports and small series. Cytology-based publications of CN are rare. Here, we report a case of CN in a 22-year-old girl. Intra-operative squash cytology and subsequent histopathology of the tumor simulated an oligodendroglioma and a clear cell ependydoma. Final confirmation was obtained on immunohistochemistry. This paper discusses the salient cytological, histomorphological and immunohistochemical features of CN that are useful in distinguishing from its mimickers.


Central neurocytoma; immunohistochemistry; squash cytology

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