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J Cytol. 2011 Oct;28(4):219-22. doi: 10.4103/0970-9371.86357.

Intraoperative cytology of central neurocytoma mimicking oligodendroglioma.

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  • 1Department of Pathology, Armed Forces Medical College, Pune, India.

Abstract

Central neurocytomas (CNs) are uncommon tumors of the central nervous system. These tumors have a predilection for the lateral ventricles of young adults and are known to display characteristic neuroimaging and histomorphologic features. Typically, CNs are associated with a favorable outcome, although cases with more aggressive clinical course with recurrences are not unknown. Most descriptions of this tumor are available in the form of isolated histopathology-based case reports and small series. Cytology-based publications of CN are rare. Here, we report a case of CN in a 22-year-old girl. Intra-operative squash cytology and subsequent histopathology of the tumor simulated an oligodendroglioma and a clear cell ependydoma. Final confirmation was obtained on immunohistochemistry. This paper discusses the salient cytological, histomorphological and immunohistochemical features of CN that are useful in distinguishing from its mimickers.

KEYWORDS:

Central neurocytoma; immunohistochemistry; squash cytology

PMID:
22090702
[PubMed]
PMCID:
PMC3214473
Free PMC Article
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