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Case Rep Oncol. 2011 Sep;4(3):452-7. doi: 10.1159/000332044. Epub 2011 Sep 7.

An unusual case of locally advanced glycogen-rich clear cell carcinoma of the breast.

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  • 1Departments of Radiology, Virgen de la Arrixaca University Hospital, Murcia, Spain.


Glycogen-rich clear cell (GRCC) is a rare subtype of breast carcinoma characterized by carcinoma cells containing an optically clear cytoplasm and intracytoplasmic glycogen. We present the case of a 55-year-old woman with a palpable mass in the right breast and clinical signs of locally advanced breast cancer (LABC). The diagnosis of GRCC carcinoma was based on certain histopathological characteristics of the tumor and immunohistochemical analysis. To our knowledge, this is the first case of GRCC LABC with intratumoral calcifications. There is no evidence of recurrence or metastatic disease after 14 months' follow-up.


Glycogen-rich clear cell carcinoma; Locally advanced breast cancer; Mammography; Ultrasonography

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