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Nucleic Acids Res. 2012 Jan;40(Database issue):D735-41. doi: 10.1093/nar/gkr954. Epub 2011 Nov 8.

WormBase 2012: more genomes, more data, new website.

Author information

  • 1Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA. kyook@wormbase.org

Abstract

Since its release in 2000, WormBase (http://www.wormbase.org) has grown from a small resource focusing on a single species and serving a dedicated research community, to one now spanning 15 species essential to the broader biomedical and agricultural research fields. To enhance the rate of curation, we have automated the identification of key data in the scientific literature and use similar methodology for data extraction. To ease access to the data, we are collaborating with journals to link entities in research publications to their report pages at WormBase. To facilitate discovery, we have added new views of the data, integrated large-scale datasets and expanded descriptions of models for human disease. Finally, we have introduced a dramatic overhaul of the WormBase website for public beta testing. Designed to balance complexity and usability, the new site is species-agnostic, highly customizable, and interactive. Casual users and developers alike will be able to leverage the public RESTful application programming interface (API) to generate custom data mining solutions and extensions to the site. We report on the growth of our database and on our work in keeping pace with the growing demand for data, efforts to anticipate the requirements of users and new collaborations with the larger science community.

PMID:
22067452
[PubMed - indexed for MEDLINE]
PMCID:
PMC3245152
Free PMC Article
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