The creation of the European Higher Education Area has brought the relevance of the scientific quality assessment in higher education. The result of this interest is a growing interest in the development of rankings of universities, both nationally and internationally. To continue the line started two years ago, the goal of this research is to update the ranking of research productivity in Spanish public universities with the data of 2010. We follow the same methodology to data from 2008 and 2009; although this year it includes measures of total production. The same indicators to evaluate research in 2009: journals articles indexed in the JCR, research periods, research + development projects, doctoral dissertations, grants for training university teachers, Doctoral Programs with Quality Mention and patents. From the results obtained show that universities with higher production were Complutense de Madrid, Barcelona and Granada. The most productive were the Pompeu Fabra University, the Pablo de Olavide, and the Autonoma de Barcelona.