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Complement Ther Med. 2011 Dec;19(6):311-8. doi: 10.1016/j.ctim.2011.08.004. Epub 2011 Sep 15.

The effects of Lyprinol(®) on delayed onset muscle soreness and muscle damage in well trained athletes: a double-blind randomised controlled trial.

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  • 1National Institute of Sport Studies, University of Canberra, Australia. Kate.Pumpa@canberra.edu.au

Abstract

OBJECTIVES:

The aim of the study was to determine if Lyprinol(®) is effective in reducing pain, indicators of inflammation and muscle damage, and in turn improving performance in well trained athletes suffering from delayed onset muscle soreness (DOMS).

DESIGN:

A double blind randomised placebo controlled trial.

SETTING:

Twenty well trained male volunteers, matched by VO(2max) were randomly assigned to consume 200mg of Lyprinol(®) or an indistinguishable placebo daily for 8 weeks prior to a downhill treadmill running episode designed to induce DOMS.

MAIN OUTCOME MEASURES:

Performance measures (Kin-Com, counter movement and squat jump), pain assessments (visual analogue scale, algometer) and blood analyses (Interleukin-1, Interleukin-6, Interleukin-10, tumour necrosis factor-α, C-reactive protein, myoglobin, creatine kinase) were assessed at 7 time points over 5 days (pre, post, 4, 24, 48, 72 and 96h after the downhill run).

RESULTS:

No statistically significant differences were identified in any parameters between the active and placebo groups at any time point.

CONCLUSION:

After 2 months ingestion of Lyprinol(®) at the currently recommended dosage (200mg/day) and a demanding eccentric exercise intervention, Lyprinol(®) did not convincingly affect DOMS and indicators of muscle damage.

Copyright © 2011 Elsevier Ltd. All rights reserved.

PMID:
22036523
[PubMed - indexed for MEDLINE]
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