J Clin Pharmacol. 1990 Jul;30(7):596-608.

Co-enzyme Q10: a new drug for cardiovascular disease.

Source

Department of Medicine, Mt. Sinai Hospital and Medical Center, New York, New York.

Abstract

Co-enzyme Q10 (ubiquinone) is a naturally occurring substance which has properties potentially beneficial for preventing cellular damage during myocardial ischemia and reperfusion. It plays a role in oxidative phosphorylation and has membrane stabilizing activity. The substance has been used in oral form to treat various cardiovascular disorders including angina pectoris, hypertension, and congestive heart failure. Its clinical importance is now being established in clinical trails worldwide.

PMID:: 2202752; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Medical

ClinicalTrials.gov

Molecular Biology Databases

DOXORUBICIN - HSDB

Supplemental Content

Save items

Related citations in PubMed

Review Coenzyme Q10: a new drug for myocardial ischemia? [Med Clin North Am. 1988]
Review Coenzyme Q10: a new drug for myocardial ischemia?
Greenberg SM, Frishman WH. Med Clin North Am. 1988 Jan; 72(1):243-58.
Review Coenzyme Q in cardiovascular disease. [J Assoc Physicians India. 1998]
Review Coenzyme Q in cardiovascular disease.
Singh RB, Niaz MA, Rastogi V, Rastogi SS. J Assoc Physicians India. 1998 Mar; 46(3):299-306.
Review Overview of the use of CoQ10 in cardiovascular disease. [Biofactors. 1999]
Review Overview of the use of CoQ10 in cardiovascular disease.
Langsjoen PH, Langsjoen AM. Biofactors. 1999; 9(2-4):273-84.
Review [Coenzyme Q10 (ubiquinone) in the treatment of heart failure. Are any positive effects documented?]. [Tidsskr Nor Laegeforen. 1994]
Review [Coenzyme Q10 (ubiquinone) in the treatment of heart failure. Are any positive effects documented?].
Spigset O. Tidsskr Nor Laegeforen. 1994 Mar 20; 114(8):939-42.
Review Coenzyme Q10 in cardiovascular disease. [Mitochondrion. 2007]
Review Coenzyme Q10 in cardiovascular disease.
Pepe S, Marasco SF, Haas SJ, Sheeran FL, Krum H, Rosenfeldt FL. Mitochondrion. 2007 Jun; 7 Suppl:S154-67. Epub 2007 Mar 16.

See reviews... See all...

Cited by 4 PubMed Central articles

Fermented wheat germ extract (avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats. [Evid Based Complement Alternat...]
Fermented wheat germ extract (avemar) in the treatment of cardiac remodeling and metabolic symptoms in rats.
Iyer A, Brown L. Evid Based Complement Alternat Med. 2011; 2011:508957. Epub 2011 Jan 4.
Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. [J Int Soc Sports Nutr. 2008]
Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals.
Cooke M, Iosia M, Buford T, Shelmadine B, Hudson G, Kerksick C, Rasmussen C, Greenwood M, Leutholtz B, Willoughby D, et al. J Int Soc Sports Nutr. 2008 Mar 4; 5:8. Epub 2008 Mar 4.
Estrogen, mitochondria, and growth of cancer and non-cancer cells. [J Carcinog. 2005]
Estrogen, mitochondria, and growth of cancer and non-cancer cells.
Felty Q, Roy D. J Carcinog. 2005 Jan 15; 4(1):1. Epub 2005 Jan 15.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Co-enzyme Q10: a new drug for cardiovascular disease.
Co-enzyme Q10: a new drug for cardiovascular disease.
J Clin Pharmacol. 1990 Jul ;30(7):596-608.

PubMed
Increased risk of secondary uterine leiomyosarcoma in hereditary retinoblastoma.
Increased risk of secondary uterine leiomyosarcoma in hereditary retinoblastoma.
Gynecol Oncol. 2012 Feb ;124(2):254-9. Epub 2011 Oct 23 .

PubMed
Microarray analysis of peripheral blood lymphocytes from ALS patients and the SA...
Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway.
BMC Med Genomics. 2011 Oct 25 ;4:74.

PubMed
New directions in migraine.
New directions in migraine.
BMC Med. 2011 Oct 25 ;9:116.

PubMed
Dental caries-associated risk factors and type 1 diabetes mellitus.
Dental caries-associated risk factors and type 1 diabetes mellitus.
Pediatr Endocrinol Diabetes Metab. 2011 ;17(3):152-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Co-enzyme Q10: a new drug for cardiovascular disease.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Cited by 4 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information