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Cytojournal. 2011;8:17. doi: 10.4103/1742-6413.85496. Epub 2011 Sep 27.

Cyto-morphological features of extramedullary acute megakaryoblastic leukemia on fine needle aspiration and cerebrospinal fluid cytology: A case report.

Author information

  • 1Department of Pathology, All India Institute of Medical Sciences, New Delhi- 110 029, India.

Abstract

Extramedullary deposits may be the presenting feature of acute myeloid leukemia. An early and accurate diagnosis on cytology will aid in correct patient management. This is especially true for patients with acute megakaryoblastic leukemia (AML M7), where bone marrow aspiration may yield only a dry tap. While cytomorphological features of myeloid sarcoma of other types are well recognized due to its rarity, there are only two case reports discussing the morphological details of megakaryoblastic differentiation on aspiration cytology. We present the case of a 25-year-old patient with extramedullary involvement of lymph node and cerebrospinal fluid by AML M7, describing in detail, the morphological features on aspiration as well as exfoliative cytology.

KEYWORDS:

AML M7; cytology; extramedullary; fine needle aspiration (FNA) cytology/biopsy (FNAC)/(FNAB); leukemia; megakaryoblastic

PMID:
22022337
[PubMed]
PMCID:
PMC3193611
Free PMC Article

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