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    Eur Heart J. 2011 Dec;32(23):2922-32. doi: 10.1093/eurheartj/ehr373. Epub 2011 Oct 20.

    Antiplatelet agents for the treatment and prevention of atherothrombosis.

    Source

    Department of Pharmacology, Catholic University School of Medicine, Rome, Italy. carlo.patrono@rm.unicatt.it

    Abstract

    The clinical pharmacology of antiplatelet drugs has been reviewed previously by the European Society of Cardiology (ESC) Task force and by the 8th American College of Chest Physicians (ACCP) Evidence-Based Clinical Practice Guidelines. Moreover, information on the efficacy and safety of antiplatelet drugs in the treatment and prevention of atherothrombosis is provided by collaborative meta-analyses of 287 secondary prevention trials and 6 primary prevention trials. The present document intends to provide practicing physicians with an updated instrument to guide their choice of the most suitable antiplatelet strategy for the individual patient at risk, or with different clinical manifestations, of atherothrombosis.

    PMID:
    22019823
    [PubMed - indexed for MEDLINE]
    Free full text

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