Castleman's disease in childhood: report of three cases and review of the literature

Ital J Pediatr. 2011 Oct 20:37:50. doi: 10.1186/1824-7288-37-50.

Abstract

Castleman's disease (CD) is a rare, localized or generalized, lymphoproliferative disorder with a frequent mediastinal location, but possible in any lymph node or extra nodal site. It usually appears in young adults whilst it rarely occurs in childhood. There are only about 100 pediatric cases published, five of them in Italy. We report 3 cases of localized Castleman's disease, investigated in our Department in a 3 years period and reviewed the literature.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adolescent
  • Axilla / pathology
  • Castleman Disease / diagnostic imaging*
  • Castleman Disease / pathology*
  • Castleman Disease / radiotherapy
  • Castleman Disease / surgery
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mediastinum / diagnostic imaging
  • Mediastinum / pathology
  • Neck / pathology
  • Radiography
  • Shoulder / pathology
  • Treatment Outcome