Prevalence of heart failure with preserved ejection fraction in Latin American, Middle Eastern, and North African Regions in the I PREFER study (Identification of Patients With Heart Failure and PREserved Systolic Function: an epidemiological regional study).
Adgar D, Llanquaceo M, Gomez E, Shahin S, Motamedi M, Arnaout S, Magana Serrano JA, Al-Shamiri MQ, Habib H, Al Mahmeed W, Settouti RA, Abtroune B, Achaibou R, Adgar D, Adjroud N, Agrane K, Belguedj R, Belmahdi L, Benbouabdellah B, Bendaoud AF, Benissad A, Kaddour FZ, Benkhodja MB, Benmimoune S, Beraza D, Boudrar A, Bouguessa S, Boukhroufa F, Chetih L, Daimellah F, Djeghri N, Djellaoudji A, Djouadi N, Haddak M, Hadjkali A, Hamdache N, Kadour F, Kermezli A, Kestali O, Latreche S, Lehachi S, Melbouci M, Merdjana H, Metia N, Rahli A, Remili R, Saidi M, Tazdait R, Tehmi M, Touaibia MR, Albisu G, Alfaro M, Astudillo C, Barahona F, Cobos L, Concepción R, Espejo J, Fasce F, Fuentes A, Garayar B, Gómezu J, Llancaqueo M, Medina M, Peralta J, Ramírez C, Rienbach R, Rojo P, Schumacher E, Morales LS, Neira AM, Aguilera AC, Duque JH, Giannuzi A, Gomez E, Heredia S, Jaramillo CF, Gomez NJ, Luengas C, Beltran SP, Quintero AE, Rada F, Rizcala AA, Nubia LR, Gabriel RK, Rodriguez JC, Romero HE, Silva C, Suarez RM, Torres A, Velasquez L, Delgado AL, Badawy A, El Khatib H, El Menshawy D, El Naggar W, El Rakshy Y, El Sayed Badawy A, El Fattah Furrer A, Gobran N, Kamal S, Leon K, El Ghany M, Ramsis M, Rozza A, Shahin S, Aghasadeghi K, Amin A, Piranfar MA, Babaeibeigi MA, Behzadnia N, Dastani M, Davoodi G, Forghani M, Gharouni M, Ghasemi M, Gheidari M, Ali Hojjati NA, Kasaian E, Hassani MR, Momtahen M, Motamedi MR, Pishgou B, Sadeghian S, Salarifar M, Kashani BS, Torabi B, Abbas I, Arnaout S, Chammas E, Ghanem G, Ghawi R, Khhoury W, Khoury F, Khoury R, Kishishian S, Kreidieh I, Mamlouk M, Mouawad W, Ojeimi G, Simonian A, Skouri H, Youwakim N, Zepeda CA, Grajeda JM, Acosta Valdez JL, Gil JA, Medina CA, Medina IA, Chavez JL, Ruiz AE, Ruiz B, Aguirre AB, Rivas AB, Santaolalla AS, Perez MA, Rivera AG, Cabañas Ade L, Nájera AE, Fierro OF, Chong FG, Muñoz DG, Contreras MA, Cervantes CG, García HR, Gálvez MA, Rosales CH, Cruz AJ, Juárez JH, García DK, Lara ML, Martínez ML, Velazco AL, Serrano JA, Villalon JA, Cano MA, Martinez JN, Medina JG, Abraham Pacheco Ureña AP, Michel RP, Martínez AP, Arias ER, Rodríguez GR, Chazaro ER, Cisneros FR, Hernández EA, Mariscal LR, Moctezuma RR, Avila GR, Nieves RA, Martínez DS, Nicolas NC, Zetina ES, Morales AA, Razo AS, Abdou MA, Abdulsalam MA, Samra MN, Aldosouky K, Alshaer F, Al-Shamiri MQ, Saad Mohamed Balid SM, Dogra SB, El-Bably FG, Gadalla K, El Din Helmy MS, Iftikhar S, Moustafa M, Odeh MH, Raslan H, Selim ML, Swaid K, Zaini A, Ayari M, Bahroun S, Belhani A, Boujelbene F, Boussaadia H, Chelli M, Drissa H, El Benna T, Fourati S, Grati Z, Habib H, Hassine R, Kolsi N, Mezghanni M, Mili K, Tabka M, Zaghdoudi H, Zouari S, Anil Kumar W, Alhatou E, Ali Y, Bazargani N, Binbrik A, Hallak O, Kiwan Y, Kumar A.
Source
Centro Médico Nacional Siglo XXI, Mexico City, Mexico.
Abstract
The aims of the present study were to estimate the prevalence of heart failure (HF) with preserved ejection fraction (HF-PEF) in patients with HF and to compare their clinical characteristics with those with reduced ejection fraction in non-Western countries. The left ventricular ejection fraction ≥ 45% if measured < 1 year before the visit was used to qualify the patients as having HF-PEF. Of the 2,536 consecutive outpatients with HF, 1990 (79%) had the EF values recorded. Of these patients, 1291 had HF-PEF, leading to an overall prevalence of 65% (95% confidence interval 63% to 67%). Compared to the patients with HF and a reduced ejection fraction, those with HF-PEF were more likely to be older (65 vs 62 years, p < 0.001), female (50% vs 28%, p < 0.001), and obese (39% vs 27%, p < 0.001). They more frequently had a history of hypertension (78% vs 53%, p < 0.001) and atrial fibrillation (29% vs 24%, p = 0.03) and less frequently had a history of myocardial infarction (21% vs 44%, p < 0.001). Only 29% of patients with HF-PEF and hypertension had optimal blood pressure control. Left ventricular hypertrophy was less frequent in those with HF-PEF (58% vs 69%, p < 0.001). The prevalence of HF-PEF was lower in the Middle East (41%), where coronary artery disease was more often found than in Latin America (69%) and North Africa (75%), where the rate of hypertension was greater. In conclusion, in the present diverse non-Western study, HF-PEF represented almost 2/3 of all HF cases in outpatients. HF-PEF mostly affects older patients, women, and the obese. Hypertension was the most frequently associated risk factor, highlighting the need for optimal blood pressure control.
Copyright © 2011. Published by Elsevier Inc.
- PMID:
- 22000627
- [PubMed - indexed for MEDLINE]
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