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Nat Prod Res. 2012;26(8):736-43. doi: 10.1080/14786419.2010.551752. Epub 2011 Oct 13.

Essential oil composition and antioxidant activity of different extracts of Nepeta betonicifolia C.A. Meyer and Nepeta saccharata Bunge.

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  • 1Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G.C., Evin, Tehran 1983963113, Iran. p-salehi@sbu.ac.ir

Abstract

Aerial parts essential oil of Nepeta betonicifolia and N. saccharata were obtained by hydrodistillation and analysed by GC-FID and GC-MS. Thirty-three and eighteen components represented 97.9% and 98.2% of the total oils identified, respectively. Main compounds of the oil of N. betonicifolia were 4aα,7β,7aα-nepetalactone (42.0%), germacrene D (6.0%), triplal (5.2%), 1-nor-bourbonanone (4.0%) and 1,8-cineole (3.2%). The principal constituents of the essential oil of N. saccharata were found to be 4aβ,7α,7aβ-nepetalactone (66.9%), germacrene D (12.9%), sabinene (6.5%) and trans-caryophyllene (3.3%). The radical scavenging capacity (RSC) of methanol extracts and chloroform, butanol and water subfractions of aerial parts of N. betonicifolia and N. saccharata were evaluated by using DPPH, FRAP and ABTS assays. TPC of each extract was measured using Folin-Ciocalteau. The antioxidant activity of the butanolic subfractions of both plants was higher than other extracts examined.

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