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Pol Merkur Lekarski. 2011 Sep;31(183):175-8.

[Semantic variant of the fluent primary progressive aphasia--case report].

[Article in Polish]

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  • 1Department of Neurology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine in Warsaw, Poland.


Originally progressive aphasia (primary progressive aphasia - PPA) is a specific clinical syndrom, recognized as one of three forms fronto-temporal lobar degeneration (FTLD). This group also includes fronto-temporal dementia (FTD) and semantic dementia (SD). The classification of Bonner et al distinguished three variants of PPA: logopenic, agrammatic and semantic PPA. The aim of the study was an attempt to analyze the complex, rarely recognized clinical syndrome that is primary progressive aphasia with the latest diagnostic criteria. This paper presents a case of the 55-year old woman with impaired language disorders in the form of PPA. In the diagnostic process, with repeated measurements, we used the results of physical examinations, neurological, psychological, EEG, brain imaging to the evaluation of structural and metabolic changes in MRI and PET biochemical tests of cerebrospinal fluid, without the possibility of morphological verification. Psychological assessment was performed by clinical experiment with the use of psychometric scales - WAIS-R, BVRT, Rey's figure, Stroop Test, RHLB, The Trail Making Test and clinical trials - Łucki W. Papers. Based on the latest, differential criteria for this syndrome, semantic variant of primary progressive aphasia diagnosis was made.


The use of the latest classification of a PPA seems to be an interesting proposition to improve methods for identifying, testing and treatment of this complex clinical syndrome. On each stage of the diagnostic and therapeutic process, patient required individually adjusted neuropsychological cognitive and executive functions rehabilitation.

[PubMed - indexed for MEDLINE]
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